Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy

Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy

Hair follicles (HFs) are sensitive to chemotherapy but recover from quiescent HF stem cells, although sometimes chemotherapy results in permanent loss. Here, Kim et al. establish a model of permanent chemotherapy-induced alopecia to uncover the underlying mechanisms depleting human HF stem cells.

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Detalles Bibliográficos
Autores principales: Jin Yong Kim, Jungyoon Ohn, Ji-Seon Yoon, Bo Mi Kang, Minji Park, Sookyung Kim, Woochan Lee, Sungjoo Hwang, Jong-Il Kim, Kyu Han Kim, Ohsang Kwon
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/0ebcac53511c43cd9ca4c49f28dcf1a2
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