Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).

<h4>Background</h4>Pathogenic aneuploidies involve the concept of dosage-sensitive genes leading to over- and underexpression phenotypes. Monosomy 21 in human leads to mental retardation and skeletal, immune and respiratory function disturbances. Most of the human condition corresponds t...

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Autores principales: Glòria Arqué, Vassiliki Fotaki, David Fernández, María Martínez de Lagrán, Maria L Arbonés, Mara Dierssen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/0ebf15927bdb41ad85aa87c511de0217
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