Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans
Recent human feeding studies have shown how the baseline taxonomic composition of the gut microbiome can determine responses to dietary interventions, but the exact functional determinants underlying this phenomenon remain unclear. In this study, we set out to better understand interactions between...
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American Society for Microbiology
2021
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| Acceso en línea: | https://doaj.org/article/0eca4b836dd548e399440cdff98647f6 |
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oai:doaj.org-article:0eca4b836dd548e399440cdff98647f62021-12-02T17:48:14ZBaseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans2379-507710.1128/mSystems.00964-21https://doaj.org/article/0eca4b836dd548e399440cdff98647f62021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00964-21https://doaj.org/toc/2379-5077 Recent human feeding studies have shown how the baseline taxonomic composition of the gut microbiome can determine responses to dietary interventions, but the exact functional determinants underlying this phenomenon remain unclear. In this study, we set out to better understand interactions between baseline BMI, metabolic health, diet, gut microbiome functional profiles, and subsequent weight changes in a human cohort that underwent a healthy lifestyle intervention.Christian DienerShizhen QinYong ZhouSushmita PatwardhanLi TangJennifer C. LovejoyAndrew T. MagisNathan D. PriceLeroy HoodSean M. GibbonsAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 5 (2021) |
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DOAJ |
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DOAJ |
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EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Christian Diener Shizhen Qin Yong Zhou Sushmita Patwardhan Li Tang Jennifer C. Lovejoy Andrew T. Magis Nathan D. Price Leroy Hood Sean M. Gibbons Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans |
| description |
Recent human feeding studies have shown how the baseline taxonomic composition of the gut microbiome can determine responses to dietary interventions, but the exact functional determinants underlying this phenomenon remain unclear. In this study, we set out to better understand interactions between baseline BMI, metabolic health, diet, gut microbiome functional profiles, and subsequent weight changes in a human cohort that underwent a healthy lifestyle intervention. |
| format |
article |
| author |
Christian Diener Shizhen Qin Yong Zhou Sushmita Patwardhan Li Tang Jennifer C. Lovejoy Andrew T. Magis Nathan D. Price Leroy Hood Sean M. Gibbons |
| author_facet |
Christian Diener Shizhen Qin Yong Zhou Sushmita Patwardhan Li Tang Jennifer C. Lovejoy Andrew T. Magis Nathan D. Price Leroy Hood Sean M. Gibbons |
| author_sort |
Christian Diener |
| title |
Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans |
| title_short |
Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans |
| title_full |
Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans |
| title_fullStr |
Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans |
| title_full_unstemmed |
Baseline Gut Metagenomic Functional Gene Signature Associated with Variable Weight Loss Responses following a Healthy Lifestyle Intervention in Humans |
| title_sort |
baseline gut metagenomic functional gene signature associated with variable weight loss responses following a healthy lifestyle intervention in humans |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/0eca4b836dd548e399440cdff98647f6 |
| work_keys_str_mv |
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| _version_ |
1718379449576062976 |