Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration

Abstract Zebrafish (Danio rerio) is increasingly used to assess the pharmacological activity and toxicity of compounds. The spatiotemporal distribution of seven fluorescent alkyne compounds was examined during 48 h after immersion (10 µM) or microinjection (2 mg/kg) in the pericardial cavity (PC), i...

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Autores principales: Marlly Guarin, Ruben Faelens, Arianna Giusti, Noémie De Croze, Marc Léonard, Deirdre Cabooter, Pieter Annaert, Peter de Witte, Annelii Ny
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/0eddd8ab3b4f47fd9557c755447ca0c1
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