Mechanisms of Nucleosome Reorganization by PARP1

Mechanisms of Nucleosome Reorganization by PARP1

Poly(ADP-ribose) polymerase 1 (PARP1) is an enzyme involved in DNA repair, chromatin organization and transcription. During transcription initiation, PARP1 interacts with gene promoters where it binds to nucleosomes, replaces linker histone H1 and participates in gene regulation. However, the mechan...

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Auteurs principaux: Natalya V. Maluchenko, Dmitry K. Nilov, Sergey V. Pushkarev, Elena Y. Kotova, Nadezhda S. Gerasimova, Mikhail P. Kirpichnikov, Marie-France Langelier, John M. Pascal, Md. Sohail Akhtar, Alexey V. Feofanov, Vasily M. Studitsky
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
nucleosome
poly(ADP-ribose) polymerase 1
spFRET microscopy
molecular dynamics
Biology (General)
QH301-705.5
Chemistry
QD1-999
Accès en ligne:https://doaj.org/article/0f2f4ab1755440bd8cc0c4ed3e76e9ad
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https://doaj.org/article/0f2f4ab1755440bd8cc0c4ed3e76e9ad

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