MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies

MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies

Abstract Nutritional status during gestation may lead to a phenomenon known as metabolic programming, which can be triggered by epigenetic mechanisms. The Let-7 family of microRNAs were one of the first to be discovered, and are closely related to metabolic processes. Bioinformatic analysis revealed...

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Autores principales: Laís A. P. Simino, Carolina Panzarin, Marina F. Fontana, Thais de Fante, Murilo V. Geraldo, Letícia M. Ignácio-Souza, Marciane Milanski, Marcio A. Torsoni, Michael G. Ross, Mina Desai, Adriana S. Torsoni
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/0f68b0c64c594985bf206d39b2e7bd90
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https://doaj.org/article/0f68b0c64c594985bf206d39b2e7bd90

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