Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology.
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by cortical and spinal motor neuron dysfunction. Routine magnetic resonance imaging (MRI) studies have previously shown hypointense signal in the motor cortex on T(2)-weighted images in some ALS patients, h...
Guardado en:
Autores principales: | Justin Y Kwan, Suh Young Jeong, Peter Van Gelderen, Han-Xiang Deng, Martha M Quezado, Laura E Danielian, John A Butman, Lingye Chen, Elham Bayat, James Russell, Teepu Siddique, Jeff H Duyn, Tracey A Rouault, Mary Kay Floeter |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/0f7888cfdc984453a07d2db754a8f3a8 |
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