MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation

Enhancers are often transcribed into non-coding RNAs called enhancer RNAs. Here the authors show that super enhancer generated seRNA-1 regulates the expression of nearby myoglobin (Mb) gene by binding to heterogeneous nuclear ribonucleoprotein L during myogenic differentiation.

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Autores principales: Yu Zhao, Jiajian Zhou, Liangqiang He, Yuying Li, Jie Yuan, Kun Sun, Xiaona Chen, Xichen Bao, Miguel A. Esteban, Hao Sun, Huating Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/0f7e8fe68c21423b8d3fab8d3d749d85
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