MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation

MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation

Enhancers are often transcribed into non-coding RNAs called enhancer RNAs. Here the authors show that super enhancer generated seRNA-1 regulates the expression of nearby myoglobin (Mb) gene by binding to heterogeneous nuclear ribonucleoprotein L during myogenic differentiation.

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Autores principales: Yu Zhao, Jiajian Zhou, Liangqiang He, Yuying Li, Jie Yuan, Kun Sun, Xiaona Chen, Xichen Bao, Miguel A. Esteban, Hao Sun, Huating Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/0f7e8fe68c21423b8d3fab8d3d749d85
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