Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms
14-3-3 proteins recognize phosphorylated motifs within numerous protein partners. Here, the authors characterize the binding of all human 14-3-3 isoforms to four E6 oncoproteins, and identify a fixed order of 14-3-3 binding affinities that is conserved in 14-3-3:phosphoprotein interactions across th...
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Autores principales: | Gergo Gogl, Kristina V. Tugaeva, Pascal Eberling, Camille Kostmann, Gilles Trave, Nikolai N. Sluchanko |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/1012e611587b4449b559fa63901828a2 |
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