Artificial exosomes mediated spatiotemporal-resolved and targeted delivery of epigenetic inhibitors

Abstract Background Malignant tumor is usually associated with epigenetic dysregulation, such as overexpression of histone deacetylase (HDAC), thus HDAC has emerged as a therapeutic target for cancer. Histone deacetylase inhibitor has been approved for clinical use to treat hematological cancers. Ho...

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Autores principales: Huan Li, Songpei Li, Yinshan Lin, Sheng Chen, Langyu Yang, Xin Huang, Hao Wang, Xiyong Yu, Lingmin Zhang
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/1046fadceb8a4fc7ab61b69c4b80c7ce
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