Artificial exosomes mediated spatiotemporal-resolved and targeted delivery of epigenetic inhibitors
Abstract Background Malignant tumor is usually associated with epigenetic dysregulation, such as overexpression of histone deacetylase (HDAC), thus HDAC has emerged as a therapeutic target for cancer. Histone deacetylase inhibitor has been approved for clinical use to treat hematological cancers. Ho...
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Auteurs principaux: | Huan Li, Songpei Li, Yinshan Lin, Sheng Chen, Langyu Yang, Xin Huang, Hao Wang, Xiyong Yu, Lingmin Zhang |
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Format: | article |
Langue: | EN |
Publié: |
BMC
2021
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Accès en ligne: | https://doaj.org/article/1046fadceb8a4fc7ab61b69c4b80c7ce |
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