Heterozygous diploid and interspecies SCRaMbLEing

Heterozygous diploid and interspecies SCRaMbLEing

SCRaMbLE has been used to rearrange synthetic chromosomes that have been introduced into host yeast. Here the authors produce semi-synthetic heterozygous diploid strains for rapid selection of phenotypes and map the rearrangements underlying selected phenotypes such as thermoresistance and caffeine...

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Bibliographic Details
Main Authors: Michael J. Shen, Yi Wu, Kun Yang, Yunxiang Li, Hui Xu, Haoran Zhang, Bing-Zhi Li, Xia Li, Wen-Hai Xiao, Xiao Zhou, Leslie A. Mitchell, Joel S. Bader, Yingjin Yuan, Jef D. Boeke
Format: article
Language:EN
Published: Nature Portfolio 2018
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Science
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Online Access:https://doaj.org/article/10854cf705494aad9131a27d7390c08c
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https://doaj.org/article/10854cf705494aad9131a27d7390c08c

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