Polymyxin Combinations Combat <italic toggle="yes">Escherichia coli</italic> Harboring <italic toggle="yes">mcr-1</italic> and <italic toggle="yes">bla</italic><sub>NDM-5</sub>: Preparation for a Postantibiotic Era

Polymyxin Combinations Combat <italic toggle="yes">Escherichia coli</italic> Harboring <italic toggle="yes">mcr-1</italic> and <italic toggle="yes">bla</italic><sub>NDM-5</sub>: Preparation for a Postantibiotic Era

ABSTRACT The rapid increase of carbapenem resistance in Gram-negative bacteria has resurrected the importance of the polymyxin antibiotics. The recent discovery of plasmid-mediated polymyxin resistance (mcr-1) in carbapenem-resistant Enterobacteriaceae serves as an important indicator that the golde...

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Bibliographic Details
Main Authors: Zackery P. Bulman, Liang Chen, Thomas J. Walsh, Michael J. Satlin, Yuli Qian, Jürgen B. Bulitta, Charles A. Peloquin, Patricia N. Holden, Roger L. Nation, Jian Li, Barry N. Kreiswirth, Brian T. Tsuji
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
Enterobacteriaceae
MCR-1
NDM-5
amikacin
aztreonam
carbapenem-resistant
Microbiology
QR1-502
Online Access:https://doaj.org/article/109d08cddec34fa99f3d35936c35c8dc
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