Phasevarion mediated epigenetic gene regulation in Helicobacter pylori.

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae and pathogenic Neisseria, the random switching of the modA gene, associated with a...

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Autores principales: Yogitha N Srikhanta, Rebecca J Gorrell, Jason A Steen, Jayde A Gawthorne, Terry Kwok, Sean M Grimmond, Roy M Robins-Browne, Michael P Jennings
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/10a05969ff9a4e6fb4c611f41657e2d3
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