Direct amidation of esters with nitroarenes

Direct conversion of esters to amides, while attractive, is often limited to activated esters or highly nucleophilic amines. Here the authors report a nickel-catalysed reductive coupling between unactivated esters and nitroarenes, giving a direct route to aromatic amides.

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Auteurs principaux: Chi Wai Cheung, Marten Leendert Ploeger, Xile Hu
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/10b081dbcf634db29252db615d5ffd3a
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