Direct amidation of esters with nitroarenes

Direct conversion of esters to amides, while attractive, is often limited to activated esters or highly nucleophilic amines. Here the authors report a nickel-catalysed reductive coupling between unactivated esters and nitroarenes, giving a direct route to aromatic amides.

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Detalles Bibliográficos
Autores principales: Chi Wai Cheung, Marten Leendert Ploeger, Xile Hu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/10b081dbcf634db29252db615d5ffd3a
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