The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function

Abstract Mitochondria have a remarkable ability to uptake and store massive amounts of calcium. However, the consequences of massive calcium accumulation remain enigmatic. In the present study, we analyzed a series of time-course experiments to identify the sequence of events that occur in a populat...

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Auteurs principaux: Jasiel O. Strubbe-Rivera, Jason R. Schrad, Evgeny V. Pavlov, James F. Conway, Kristin N. Parent, Jason N. Bazil
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/10be602351054d3e97056f991fc7d5e6
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