PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis

Abstract Protein arginine methyltransferase 1 (PRMT1) is able to promote breast cancer cell proliferation. However, the detailed mechanisms of PRMT1-mediated breast cancer cell proliferation are largely unknown. In this study, we reveal that PRMT1-mediated methylation of EZH2 at the R342 site (meR34...

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Autores principales: Zhongwei Li, Diandian Wang, Xintian Chen, Wenwen Wang, Pengfei Wang, Pingfu Hou, Minle Li, Sufang Chu, Shuxi Qiao, Junnian Zheng, Jin Bai
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/10f93ae2b56e468c977ccd8ea25e918e
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