Curvotaxis directs cell migration through cell-scale curvature landscapes

Curvotaxis directs cell migration through cell-scale curvature landscapes

The effect that microscale surface curvature has on cell migration has not been evaluated. Here the authors fabricate sinusoidal 3D surfaces and show that the cell nucleus and cytoskeleton cooperate to guide cells to concave valleys in a process they coin curvotaxis.

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Detalles Bibliográficos
Autores principales: Laurent Pieuchot, Julie Marteau, Alain Guignandon, Thomas Dos Santos, Isabelle Brigaud, Pierre-François Chauvy, Thomas Cloatre, Arnaud Ponche, Tatiana Petithory, Pablo Rougerie, Maxime Vassaux, Jean-Louis Milan, Nayana Tusamda Wakhloo, Arnaud Spangenberg, Maxence Bigerelle, Karine Anselme
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/110d3deece5b4a78ab42eb5f8f125038
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Internet

https://doaj.org/article/110d3deece5b4a78ab42eb5f8f125038

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