A Noncanonical DNA Damage Checkpoint Response in a Major Fungal Pathogen

ABSTRACT DNA damage checkpoints are key guardians of genome integrity. Eukaryotic cells respond to DNA damage by triggering extensive phosphorylation of Rad53/CHK2 effector kinase, whereupon activated Rad53/CHK2 mediates further aspects of checkpoint activation, including cell cycle arrest and trans...

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Bibliographic Details
Main Authors: Erika Shor, Rocio Garcia-Rubio, Lucius DeGregorio, David S. Perlin
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/113116fc5724411bb8d05db9c7e920c6
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