A Noncanonical DNA Damage Checkpoint Response in a Major Fungal Pathogen
ABSTRACT DNA damage checkpoints are key guardians of genome integrity. Eukaryotic cells respond to DNA damage by triggering extensive phosphorylation of Rad53/CHK2 effector kinase, whereupon activated Rad53/CHK2 mediates further aspects of checkpoint activation, including cell cycle arrest and trans...
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Autores principales: | Erika Shor, Rocio Garcia-Rubio, Lucius DeGregorio, David S. Perlin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/113116fc5724411bb8d05db9c7e920c6 |
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