Direct bacterial killing in vitro by recombinant Nod2 is compromised by Crohn's disease-associated mutations.
<h4>Background</h4>A homeostatic relationship with the intestinal microflora is increasingly appreciated as essential for human health and wellbeing. Mutations in the leucine-rich repeat (LRR) domain of Nod2, a bacterial recognition protein, are associated with development of the inflamm...
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Autores principales: | , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2010
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Acceso en línea: | https://doaj.org/article/1133fe159fb844d2877b522597347e56 |
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