TERT genetic variability and telomere length as factors affecting survival and risk in acute myeloid leukaemia

Abstract Acute myeloid leukaemia (AML) is a neoplasm of immature myeloid cells characterized by various cytogenetic alterations. The present study showed that in addition to the FLT3-ITD and NPM1 mutation status, telomere length (TL) and telomerase reverse transcriptase (TERT) gene polymorphisms may...

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Autores principales: Marta Dratwa, Barbara Wysoczańska, Aleksandra Butrym, Piotr Łacina, Grzegorz Mazur, Katarzyna Bogunia-Kubik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/11385e314e404688906129966ec49594
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