TERT genetic variability and telomere length as factors affecting survival and risk in acute myeloid leukaemia

TERT genetic variability and telomere length as factors affecting survival and risk in acute myeloid leukaemia

Abstract Acute myeloid leukaemia (AML) is a neoplasm of immature myeloid cells characterized by various cytogenetic alterations. The present study showed that in addition to the FLT3-ITD and NPM1 mutation status, telomere length (TL) and telomerase reverse transcriptase (TERT) gene polymorphisms may...

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Autores principales: Marta Dratwa, Barbara Wysoczańska, Aleksandra Butrym, Piotr Łacina, Grzegorz Mazur, Katarzyna Bogunia-Kubik
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/11385e314e404688906129966ec49594
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