Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

The BRCA2 tumour suppressor protein is known to play an important role in homologous recombination. Here the authors reveal how the phosphorylation of BRCA2 by Polo-like kinase 1 (PLK1) contributes to the regulation of mitosis.

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Autores principales: Åsa Ehlén, Charlotte Martin, Simona Miron, Manon Julien, François-Xavier Theillet, Virginie Ropars, Gaetana Sessa, Romane Beaurepere, Virginie Boucherit, Patricia Duchambon, Ahmed El Marjou, Sophie Zinn-Justin, Aura Carreira
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/1172298aed5c403d86de4c53b25b80bd
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https://doaj.org/article/1172298aed5c403d86de4c53b25b80bd

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