CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.
Cytotoxic CD8+ T cells (CTLs) play a critical role in controlling viral infections. HIV-infected individuals develop CTL responses against epitopes derived from viral proteins, but also against cryptic epitopes encoded by viral alternative reading frames (ARF). We studied here the mechanisms of HIV-...
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Auteurs principaux: | , , , , , , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
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Accès en ligne: | https://doaj.org/article/11741e79371a421faecf68c1ab9f787a |
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