CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.
Cytotoxic CD8+ T cells (CTLs) play a critical role in controlling viral infections. HIV-infected individuals develop CTL responses against epitopes derived from viral proteins, but also against cryptic epitopes encoded by viral alternative reading frames (ARF). We studied here the mechanisms of HIV-...
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Autores principales: | Sylvain Cardinaud, Gesa Consiglieri, Romain Bouziat, Alejandra Urrutia, Stéphanie Graff-Dubois, Slim Fourati, Isabelle Malet, Julien Guergnon, Amélie Guihot, Christine Katlama, Brigitte Autran, Peter van Endert, François A Lemonnier, Victor Appay, Olivier Schwartz, Peter M Kloetzel, Arnaud Moris |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/11741e79371a421faecf68c1ab9f787a |
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