Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Nutrient Auxotrophy

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Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Nutrient Auxotrophy

ABSTRACT Multidrug-resistant (MDR) tuberculosis, defined as tuberculosis resistant to the two first-line drugs isoniazid and rifampin, poses a serious problem for global tuberculosis control strategies. Lack of a safe and convenient model organism hampers progress in combating the spread of MDR stra...

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Autores principales:	Catherine Vilchèze, Jacqueline Copeland, Tracy L. Keiser, Torin Weisbrod, Jacqueline Washington, Paras Jain, Adel Malek, Brian Weinrick, William R. Jacobs
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2018
Materias:	Mycobacterium tuberculosis arginine auxotrophy methionine multidrug resistance Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/117a19d7561c4ccb89b01386464f0034
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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