Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Nutrient Auxotrophy
ABSTRACT Multidrug-resistant (MDR) tuberculosis, defined as tuberculosis resistant to the two first-line drugs isoniazid and rifampin, poses a serious problem for global tuberculosis control strategies. Lack of a safe and convenient model organism hampers progress in combating the spread of MDR stra...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/117a19d7561c4ccb89b01386464f0034 |
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