Rational Design of Biosafety Level 2-Approved, Multidrug-Resistant Strains of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Nutrient Auxotrophy
ABSTRACT Multidrug-resistant (MDR) tuberculosis, defined as tuberculosis resistant to the two first-line drugs isoniazid and rifampin, poses a serious problem for global tuberculosis control strategies. Lack of a safe and convenient model organism hampers progress in combating the spread of MDR stra...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2018
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/117a19d7561c4ccb89b01386464f0034 |
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