Multimodal, label-free fluorescence and Raman imaging of amyloid deposits in snap-frozen Alzheimer’s disease human brain tissue

Lochocki et al. report detection of amyloid plaques by label-free fluorescence and Raman imaging in snap-frozen frontal cortex tissue from Alzheimer’s disease cases. They identify presence of carotenoid in a cored amyloid plaque area, versus a non-plaque area, suggesting a distinct neuroinflammatory...

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Auteurs principaux: Benjamin Lochocki, Baayla D. C. Boon, Sander R. Verheul, Liron Zada, Jeroen J. M. Hoozemans, Freek Ariese, Johannes F. de Boer
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/117dde8786184e2c8fb9f7c360ba1851
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