Salmonella Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli

Curli amyloid fibers are important components of bacterial biofilms formed by E. coli and Salmonella. Here, Tursi et al. show that a human monoclonal antibody with pan-amyloid binding activity can disrupt biofilms formed by Salmonella Typhimurium in vitro and in vivo.

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Autores principales: Sarah A. Tursi, Rama Devudu Puligedda, Paul Szabo, Lauren K. Nicastro, Amanda L. Miller, Connie Qiu, Stefania Gallucci, Norman R. Relkin, Bettina A. Buttaro, Scott K. Dessain, Çagla Tükel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/11897af34d794b4a87d6cb813eff5536
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