Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Tuberculosis meningitis (TBM) is a severe form of TB with limited treatment options. Here, the authors perform RNA sequencing on whole blood and on ventricular and lumbar cerebrospinal fluid (CSF) samples from pediatric patients treated for TBM to characterize the immune response and tissue damage.
Saved in:
Main Authors: | Ursula K. Rohlwink, Anthony Figaji, Katalin A. Wilkinson, Stuart Horswell, Abdul K. Sesay, Armin Deffur, Nico Enslin, Regan Solomons, Ronald Van Toorn, Brian Eley, Michael Levin, Robert J. Wilkinson, Rachel P. J. Lai |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/11b7cc57037a47a2b99a6a49c4d9e072 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tuberculous Meningitis
by: Vernal S,Patricia, et al.
Published: (1986) -
Tuberculous Meningitis: The Important Role of Imaging
by: Ana Pereira Lemos, et al.
Published: (2021) -
Diagnostic Model for Discrimination Between Tuberculous Meningitis and Bacterial Meningitis
by: Ying Luo, et al.
Published: (2021) -
COMPARATIVE ANALYSIS OF CEREBROSPINAL FLUID ADA LEVELS IN TUBERCULOUS AND NON-TUBERCULOUS MENINGITIS
by: Zahid Ullah, et al.
Published: (2018) -
Risk factors for poor outcome in childhood tuberculous meningitis
by: Mao-Shui Wang, et al.
Published: (2021)