Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy

The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.

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Main Authors:	Fabian U. Zwettler, Marie-Christin Spindler, Sebastian Reinhard, Teresa Klein, Andreas Kurz, Ricardo Benavente, Markus Sauer
Format:	article
Language:	EN
Published:	Nature Portfolio 2020
Subjects:	Science Q
Online Access:	https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c
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spelling	oai:doaj.org-article:11cb7bca60d54e4b80ed2a6bc218b85c2021-12-02T17:12:24ZTracking down the molecular architecture of the synaptonemal complex by expansion microscopy10.1038/s41467-020-17017-72041-1723https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c2020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17017-7https://doaj.org/toc/2041-1723The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.Fabian U. ZwettlerMarie-Christin SpindlerSebastian ReinhardTeresa KleinAndreas KurzRicardo BenaventeMarkus SauerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fabian U. Zwettler Marie-Christin Spindler Sebastian Reinhard Teresa Klein Andreas Kurz Ricardo Benavente Markus Sauer Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
description	The authors test expansion microscopy protocols for investigation of the molecular organisation of mammalian synaptonemal complexes (SCs) with structured illumination microscopy. They show that the molecular structure is preserved during expansion and ultrastructural details of SCs can be revealed.
format	article
author	Fabian U. Zwettler Marie-Christin Spindler Sebastian Reinhard Teresa Klein Andreas Kurz Ricardo Benavente Markus Sauer
author_facet	Fabian U. Zwettler Marie-Christin Spindler Sebastian Reinhard Teresa Klein Andreas Kurz Ricardo Benavente Markus Sauer
author_sort	Fabian U. Zwettler
title	Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_short	Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_full	Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_fullStr	Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_full_unstemmed	Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
title_sort	tracking down the molecular architecture of the synaptonemal complex by expansion microscopy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/11cb7bca60d54e4b80ed2a6bc218b85c
work_keys_str_mv	AT fabianuzwettler trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy AT mariechristinspindler trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy AT sebastianreinhard trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy AT teresaklein trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy AT andreaskurz trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy AT ricardobenavente trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy AT markussauer trackingdownthemoleculararchitectureofthesynaptonemalcomplexbyexpansionmicroscopy
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Tracking down the molecular architecture of the synaptonemal complex by expansion microscopy

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