Designing antifilarial drug trials using clinical trial simulators

Drugs for filariases are under development and clinical trial simulators could help to inform the design of clinical trials. Here, Walker et al. use an individual-based onchocerciasis transmission model to project trial outcomes of a hypothetical macrofilaricidal drug, resolving key design choices.

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Autores principales: Martin Walker, Jonathan I. D. Hamley, Philip Milton, Frédéric Monnot, Belén Pedrique, Maria-Gloria Basáñez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/11d40320cabe405db511497a47479856
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