Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans.

Ceramide and its metabolites constitute a diverse group of lipids, which play important roles as structural entities of biological membranes as well as regulators of cellular growth, differentiation, and development. The C. elegans genome comprises three ceramide synthase genes; hyl-1, hyl-2, and la...

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Auteurs principaux: Mai-Britt Mosbech, Rikke Kruse, Eva Bang Harvald, Anne Sofie Braun Olsen, Sandra Fernandez Gallego, Hans Kristian Hannibal-Bach, Christer S Ejsing, Nils J Færgeman
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/123aa8c456f54949a4d4d820ae3406a6
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