Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans.

Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans.

Ceramide and its metabolites constitute a diverse group of lipids, which play important roles as structural entities of biological membranes as well as regulators of cellular growth, differentiation, and development. The C. elegans genome comprises three ceramide synthase genes; hyl-1, hyl-2, and la...

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Autores principales: Mai-Britt Mosbech, Rikke Kruse, Eva Bang Harvald, Anne Sofie Braun Olsen, Sandra Fernandez Gallego, Hans Kristian Hannibal-Bach, Christer S Ejsing, Nils J Færgeman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/123aa8c456f54949a4d4d820ae3406a6
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