Cannabidiol Suppresses Angiogenesis and Stemness of Breast Cancer Cells by Downregulation of Hypoxia-Inducible Factors-1α

Cannabidiol Suppresses Angiogenesis and Stemness of Breast Cancer Cells by Downregulation of Hypoxia-Inducible Factors-1α

To assess the effect of Cannabidiol (CBD) on the angiogenesis and stemness of breast cancer cells as well as proliferation. Methods: mRNA level and the amount of protein of vascular endothelial growth factor (VEGF) were determined by qRT-PCR and ELISA. The angiogenic potential of breast cancer cells...

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Bibliographic Details
Main Authors: Min Jee Jo, Bu Gyeom Kim, Woo Young Kim, Dae-Hee Lee, Hye Kyeong Yun, Soyeon Jeong, Seong Hye Park, Bo Ram Kim, Jung Lim Kim, Dae Yeong Kim, Sun Il Lee, Sang Cheul Oh
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
cannabidiol
HIF-1α
angiogenesis
stemness
breast cancer
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Online Access:https://doaj.org/article/12445ac0a3c34ec1955936b51afebb73
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https://doaj.org/article/12445ac0a3c34ec1955936b51afebb73

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