Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution

Nuclear envelope transmembrane proteins (NETs) can reside in the outer or inner nuclear membrane, but distinguishing which membrane they reside in, and their translocation rate, is technically challenging. Here the authors develop a FRAP-based super-resolution microscopy method to obtain this inform...

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Autores principales: Krishna C Mudumbi, Eric C Schirmer, Weidong Yang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/12654410bba34692906c4ecb63070f9b
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