Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy

Proopiomelanocortin is an anti-nociceptive peptide. Here the authors show in a mouse model of diabetes, that this peptide is downregulated, which may contribute to the neuropathic pain like behaviour in these models.

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Bibliographic Details
Main Authors: Divija Deshpande, Nitin Agarwal, Thomas Fleming, Claire Gaveriaux-Ruff, Christoph S. N. Klose, Anke Tappe-Theodor, Rohini Kuner, Peter Nawroth
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/12a337286d664718a2106d167beb41bd
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