An evolutionary-network model reveals stratified interactions in the V3 loop of the HIV-1 envelope.
The third variable loop (V3) of the human immunodeficiency virus type 1 (HIV-1) envelope is a principal determinant of antibody neutralization and progression to AIDS. Although it is undoubtedly an important target for vaccine research, extensive genetic variation in V3 remains an obstacle to the de...
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Main Authors: | Art F Y Poon, Fraser I Lewis, Sergei L Kosakovsky Pond, Simon D W Frost |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2007
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Online Access: | https://doaj.org/article/12a622b4b6704e47ae2c719be2b986ed |
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