Synuclein impairs trafficking and signaling of BDNF in a mouse model of Parkinson’s disease

Abstract Recent studies have demonstrated that hyperphosphorylation of tau protein plays a role in neuronal toxicities of α-synuclein (ASYN) in neurodegenerative disease such as familial Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) and Parkinson’s disease. Using a transgenic mouse model...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Fang Fang, Wanlin Yang, Jazmin B. Florio, Edward Rockenstein, Brian Spencer, Xavier M. Orain, Stephanie X. Dong, Huayan Li, Xuqiao Chen, Kijung Sung, Robert A. Rissman, Eliezer Masliah, Jianqing Ding, Chengbiao Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
R
Q
Acceso en línea:https://doaj.org/article/12c01bf2810f488c9d8ecb8510422e17
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!