MYC regulates metabolism through vesicular transfer of glycolytic kinases
Amplification of the proto-oncogene MYCN is a key molecular aberration in high-risk neuroblastoma and predictive of poor outcome in this childhood malignancy. We investigated the role of MYCN in regulating the protein cargo of extracellular vesicles (EVs) secreted by tumour cells that can be interna...
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Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
The Royal Society
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/12d0e9b553254367b95d2b65de857eae |
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