MYC regulates metabolism through vesicular transfer of glycolytic kinases

MYC regulates metabolism through vesicular transfer of glycolytic kinases

Amplification of the proto-oncogene MYCN is a key molecular aberration in high-risk neuroblastoma and predictive of poor outcome in this childhood malignancy. We investigated the role of MYCN in regulating the protein cargo of extracellular vesicles (EVs) secreted by tumour cells that can be interna...

Full description

Saved in:
Bibliographic Details
Main Authors: Alexia Tsakaneli, Victor Corasolla Carregari, Martina Morini, Alessandra Eva, Giuliana Cangemi, Olesya Chayka, Evgeny Makarov, Sandra Bibbò, Emily Capone, Gianluca Sala, Vincenzo De Laurenzi, Evon Poon, Louis Chesler, Luisa Pieroni, Martin R. Larsen, Giuseppe Palmisano, Arturo Sala
Format: article
Language:EN
Published: The Royal Society 2021
Subjects:
extracellular vesicles
MYC
MYCN
neuroblastoma
Warburg effect
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/12d0e9b553254367b95d2b65de857eae
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/12d0e9b553254367b95d2b65de857eae

Similar Items