Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor

Summary: Myeloid-derived suppressor cells (MDSCs) enhance the proliferation of endothelial cells to stimulate angiogenesis. However, many aggressive malignant tumors do not have endothelial cell-dependent blood vessels in the early stage and instead generate microcirculation by forming vasculogenic...

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Autores principales: Yinan Li, Kailiang Qiao, Xiaoyun Zhang, Haoyang Liu, Heng Zhang, Zhiyang Li, Yanrong Liu, Tao Sun
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/12d4e99362da4897a3f0cb8d90ba9f52
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