Artemisinin Binds and Inhibits the Activity of <i>Plasmodium falciparum</i> Ddi1, a Retroviral Aspartyl Protease

Artemisinin Binds and Inhibits the Activity of <i>Plasmodium falciparum</i> Ddi1, a Retroviral Aspartyl Protease

Reduced sensitivity of the human malaria parasite, <i>Plasmodium falciparum,</i> to Artemisinin and its derivatives (ARTs) threatens the global efforts towards eliminating malaria. ARTs have been shown to cause ubiquitous cellular and genetic insults, which results in the activation of t...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Noah Machuki Onchieku, Sonam Kumari, Rajan Pandey, Vaibhav Sharma, Mohit Kumar, Arunaditya Deshmukh, Inderjeet Kaur, Asif Mohmmed, Dinesh Gupta, Daniel Kiboi, Naseem Gaur, Pawan Malhotra
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
artemisinin
<i>Plasmodium falciparum</i>
DNA damage
Ddi1
ubiquitin-proteasome pathway
enzyme inhibition
Medicine
R
Accès en ligne:https://doaj.org/article/12dac69b553b417182b3d7f7b001afec
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/12dac69b553b417182b3d7f7b001afec

Documents similaires