Identification of Aggravation-Predicting Gene Polymorphisms in Coronavirus Disease 2019 Patients Using a Candidate Gene Approach Associated With Multiple Phase Pathogenesis: A Study in a Japanese City of 1 Million People

IMPORTANCE:. The pathology caused by the coronavirus disease 2019 is mediated by host-mediated lung inflammation, driving severity, and mortality. Polymorphisms in genes encoding host inflammation and immune-related molecules may be associated with the development of serious pathologies, and identif...

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Main Authors: Naoki Tanimine, MD, PhD, Daisuke Takei, MD, Naohumi Tsukiyama, MD, Hisaaki Yoshinaka, MD, Yuki Takemoto, MD, Yuka Tanaka, PhD, Tsuyoshi Kobayashi, MD, PhD, Kazuaki Tanabe, MD, PhD, Nobuhisa Ishikawa, MD, PhD, Yoshihiro Kitahara, MD, PhD, Mafumi Okimoto, MD, Nobuaki Shime, MD, PhD, Hiroki Ohge, MD, PhD, Aya Sugiyama, MD, PhD, Tomoyuki Akita, PhD, Junko Tanaka, PhD, Hideki Ohdan, MD, PhD
Format: article
Language:EN
Published: Wolters Kluwer 2021
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Online Access:https://doaj.org/article/12e1fdf3a6344ad6aff40336c40788b1
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