Towards an arthritis flare-responsive drug delivery system

The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.

Saved in:

Bibliographic Details
Main Authors:	Nitin Joshi, Jing Yan, Seth Levy, Sachin Bhagchandani, Kai V. Slaughter, Nicholas E. Sherman, Julian Amirault, Yufeng Wang, Logan Riegel, Xueyin He, Tan Shi Rui, Michael Valic, Praveen K. Vemula, Oscar R. Miranda, Oren Levy, Ellen M. Gravallese, Antonios O. Aliprantis, Joerg Ermann, Jeffrey M. Karp
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/12e29ed0087e4d67868b51dbfbcd8c91
Tags:	Add Tag No Tags, Be the first to tag this record!

id	oai:doaj.org-article:12e29ed0087e4d67868b51dbfbcd8c91
record_format	dspace
spelling	oai:doaj.org-article:12e29ed0087e4d67868b51dbfbcd8c912021-12-02T14:39:23ZTowards an arthritis flare-responsive drug delivery system10.1038/s41467-018-03691-12041-1723https://doaj.org/article/12e29ed0087e4d67868b51dbfbcd8c912018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03691-1https://doaj.org/toc/2041-1723The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.Nitin JoshiJing YanSeth LevySachin BhagchandaniKai V. SlaughterNicholas E. ShermanJulian AmiraultYufeng WangLogan RiegelXueyin HeTan Shi RuiMichael ValicPraveen K. VemulaOscar R. MirandaOren LevyEllen M. GravalleseAntonios O. AliprantisJoerg ErmannJeffrey M. KarpNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nitin Joshi Jing Yan Seth Levy Sachin Bhagchandani Kai V. Slaughter Nicholas E. Sherman Julian Amirault Yufeng Wang Logan Riegel Xueyin He Tan Shi Rui Michael Valic Praveen K. Vemula Oscar R. Miranda Oren Levy Ellen M. Gravallese Antonios O. Aliprantis Joerg Ermann Jeffrey M. Karp Towards an arthritis flare-responsive drug delivery system
description	The treatment of inflammatory arthritis by local delivery of therapeutics is limited by short half-lives of drugs. Here the authors demonstrate a hydrogel platform that titrates drug release to arthritis activity.
format	article
author	Nitin Joshi Jing Yan Seth Levy Sachin Bhagchandani Kai V. Slaughter Nicholas E. Sherman Julian Amirault Yufeng Wang Logan Riegel Xueyin He Tan Shi Rui Michael Valic Praveen K. Vemula Oscar R. Miranda Oren Levy Ellen M. Gravallese Antonios O. Aliprantis Joerg Ermann Jeffrey M. Karp
author_facet	Nitin Joshi Jing Yan Seth Levy Sachin Bhagchandani Kai V. Slaughter Nicholas E. Sherman Julian Amirault Yufeng Wang Logan Riegel Xueyin He Tan Shi Rui Michael Valic Praveen K. Vemula Oscar R. Miranda Oren Levy Ellen M. Gravallese Antonios O. Aliprantis Joerg Ermann Jeffrey M. Karp
author_sort	Nitin Joshi
title	Towards an arthritis flare-responsive drug delivery system
title_short	Towards an arthritis flare-responsive drug delivery system
title_full	Towards an arthritis flare-responsive drug delivery system
title_fullStr	Towards an arthritis flare-responsive drug delivery system
title_full_unstemmed	Towards an arthritis flare-responsive drug delivery system
title_sort	towards an arthritis flare-responsive drug delivery system
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/12e29ed0087e4d67868b51dbfbcd8c91
work_keys_str_mv	AT nitinjoshi towardsanarthritisflareresponsivedrugdeliverysystem AT jingyan towardsanarthritisflareresponsivedrugdeliverysystem AT sethlevy towardsanarthritisflareresponsivedrugdeliverysystem AT sachinbhagchandani towardsanarthritisflareresponsivedrugdeliverysystem AT kaivslaughter towardsanarthritisflareresponsivedrugdeliverysystem AT nicholasesherman towardsanarthritisflareresponsivedrugdeliverysystem AT julianamirault towardsanarthritisflareresponsivedrugdeliverysystem AT yufengwang towardsanarthritisflareresponsivedrugdeliverysystem AT loganriegel towardsanarthritisflareresponsivedrugdeliverysystem AT xueyinhe towardsanarthritisflareresponsivedrugdeliverysystem AT tanshirui towardsanarthritisflareresponsivedrugdeliverysystem AT michaelvalic towardsanarthritisflareresponsivedrugdeliverysystem AT praveenkvemula towardsanarthritisflareresponsivedrugdeliverysystem AT oscarrmiranda towardsanarthritisflareresponsivedrugdeliverysystem AT orenlevy towardsanarthritisflareresponsivedrugdeliverysystem AT ellenmgravallese towardsanarthritisflareresponsivedrugdeliverysystem AT antoniosoaliprantis towardsanarthritisflareresponsivedrugdeliverysystem AT joergermann towardsanarthritisflareresponsivedrugdeliverysystem AT jeffreymkarp towardsanarthritisflareresponsivedrugdeliverysystem
_version_	1718390639777808384

Towards an arthritis flare-responsive drug delivery system

Similar Items