Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages

Viruses infect cells mainly via specific receptors at the cell surface. Antibody-dependent enhancement (ADE) of infection is an alternative mechanism of infection for viruses to infect immune cells that is mediated by antibodies and IgG receptors (FcγRs).

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Auteurs principaux: Tadashi Maemura, Makoto Kuroda, Tammy Armbrust, Seiya Yamayoshi, Peter J. Halfmann, Yoshihiro Kawaoka
Format: article
Langue:EN
Publié: American Society for Microbiology 2021
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Accès en ligne:https://doaj.org/article/12e3490708e448ae89ca43a7164d8f6e
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