Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages

Viruses infect cells mainly via specific receptors at the cell surface. Antibody-dependent enhancement (ADE) of infection is an alternative mechanism of infection for viruses to infect immune cells that is mediated by antibodies and IgG receptors (FcγRs).

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Autores principales:	Tadashi Maemura, Makoto Kuroda, Tammy Armbrust, Seiya Yamayoshi, Peter J. Halfmann, Yoshihiro Kawaoka
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/12e3490708e448ae89ca43a7164d8f6e
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spelling	oai:doaj.org-article:12e3490708e448ae89ca43a7164d8f6e2021-11-03T21:52:35ZAntibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages2150-751110.1128/mBio.01987-21https://doaj.org/article/12e3490708e448ae89ca43a7164d8f6e2021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01987-21https://doaj.org/toc/2150-7511 Viruses infect cells mainly via specific receptors at the cell surface. Antibody-dependent enhancement (ADE) of infection is an alternative mechanism of infection for viruses to infect immune cells that is mediated by antibodies and IgG receptors (FcγRs).Tadashi MaemuraMakoto KurodaTammy ArmbrustSeiya YamayoshiPeter J. HalfmannYoshihiro KawaokaAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Microbiology QR1-502
spellingShingle	Microbiology QR1-502 Tadashi Maemura Makoto Kuroda Tammy Armbrust Seiya Yamayoshi Peter J. Halfmann Yoshihiro Kawaoka Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
description	Viruses infect cells mainly via specific receptors at the cell surface. Antibody-dependent enhancement (ADE) of infection is an alternative mechanism of infection for viruses to infect immune cells that is mediated by antibodies and IgG receptors (FcγRs).
format	article
author	Tadashi Maemura Makoto Kuroda Tammy Armbrust Seiya Yamayoshi Peter J. Halfmann Yoshihiro Kawaoka
author_facet	Tadashi Maemura Makoto Kuroda Tammy Armbrust Seiya Yamayoshi Peter J. Halfmann Yoshihiro Kawaoka
author_sort	Tadashi Maemura
title	Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
title_short	Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
title_full	Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
title_fullStr	Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
title_full_unstemmed	Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages
title_sort	antibody-dependent enhancement of sars-cov-2 infection is mediated by the igg receptors fcγriia and fcγriiia but does not contribute to aberrant cytokine production by macrophages
publisher	American Society for Microbiology
publishDate	2021
url	https://doaj.org/article/12e3490708e448ae89ca43a7164d8f6e
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Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages

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