Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages

Viruses infect cells mainly via specific receptors at the cell surface. Antibody-dependent enhancement (ADE) of infection is an alternative mechanism of infection for viruses to infect immune cells that is mediated by antibodies and IgG receptors (FcγRs).

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Bibliographic Details
Main Authors: Tadashi Maemura, Makoto Kuroda, Tammy Armbrust, Seiya Yamayoshi, Peter J. Halfmann, Yoshihiro Kawaoka
Format: article
Language:EN
Published: American Society for Microbiology 2021
Subjects:
Online Access:https://doaj.org/article/12e3490708e448ae89ca43a7164d8f6e
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